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Retatrutide maintenance protocols are still being worked out but a similar step-down approach to 4 to 8 mg weekly is the expected model

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This lipid-lowering drug, in addition to lipid control, is used as an adjunct therapy for reducing plasma glucose levels in T2D [183]

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Several mechanisms explain why GLP-1 RAs reduce body weight: Central appetite suppression: GLP-1 receptors in the hypothalamus and brainstem alter hunger signalling and food reward